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Relizen®
Safe, effective & non-hormonal relief of menopausal hot flashes for your patients who can't take hormones or don't want to take hormones.*
- Reduces frequency & intensity of hot flashes and night sweats
- Hormone-free and safe
- Used by more than 1 million women worldwide
Naturally powerful, scientifically validated
The proof is in the numbers. Bonafide rigorously researches and tests the safety and efficacy of our products.
of hot flashes
of hot flashes
of life
taking Relizen
We’ve unlocked the benefits of plant-based power
The ingredients in Relizen are made from a unique proprietary blend of highly purified flower pollen extract and have been shown in multiple published clinical studies to significantly improve menopausal symptoms.
Relizen is not a phytoestrogen and has no hormonal effect.¹‾³
In vitro data suggests the positive effects of Relizen on menopausal symptoms may be due to the inhibition of serotonin reuptake.⁴
Why Relizen?
Clinically effective
A randomized, double-blind, placebo-controlled trial in 54 women showed that Relizen significantly reduced hot flashes compared to placebo, with greater reductions over time ¹
Non-hormonal
Relizen relieves vasomotor symptoms with no hormonal effect* 1-3
In an in vitro study
- Relizen produced no proliferation of MCF-7 breast cancer cells, which are dependent on interaction with estrogen receptors, in contrast to 17-beta estradiol, which produced proliferation ³
In a pre-clinical study
- Relizen did not increase uterine weight even at 100x the equivalent human daily dose. In contrast, ethinyl estradiol increased uterine weight ²
In a clinical study
- Relizen showed no impact on measurements of estrogen, testosterone, FSH, and SHBG and showed no difference in breakthrough bleeding versus placebo¹
Safe and well-tolerated
Demonstrated safety in clinical trials and in real world experience
- Across multiple double-blind, placebo-controlled trials, adverse events were no different from placebo
- No inhibition of the CYP2D6 metabolic pathway, and no observed drug interactions 1,6
- Safely used by more than 1 million women in europe, where it has been available for over 15 years5
Relizen is taken as two tablets, once per day, with or without food.
Talk to your patients about Relizen
Recommend Relizen to your patients who need a safe, effective, non-hormonal treatment for their hot flashes and night sweats associated with menopause.