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Revaree®

A new approach to help any patient with vaginal atrophy. Revaree, made from hyaluronic acid, relieves symptoms of vaginal atrophy such as dryness and dyspareunia and improves overall vaginal health, all with no hormonal effect.


  • Hormone-free
  • Proven effective
  • Simple-to-use
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What is Revaree?

Revaree, made from hyaluronic acid, is a hormone-free treatment for the symptoms of vaginal atrophy such as dryness, itching and dyspareunia, formulated in an easy-to-use vaginal insert.²

The main ingredient in Revaree, hyaluronic acid, works by hydrating the vaginal mucosa, helping it regain elasticity and softness.¹ Vaginal atrophy affects many women, yet only a small percentage seek treatment. Improve your patients' vaginal health and quality of life with Revaree, your hormone-free solution for the treatment of vaginal atrophy.

The relief your patients need for everyday comfort and intimacy

How Revaree Works

Revaree consists of hyaluronic acid, which is a natural component of the extracellular matrix produced by the body and responsible for maintaining hydration and tissue repair. When applied topically to the vagina, hyaluronic acid hydrates the vaginal mucosa, helping regain elasticity and softness.

Pre-clinical data has demonstrated hyaluronic acid is effective in the reversal of vaginal atrophy by promoting the creation of new blood vessels which improve the vaginal epithelium's ability to repair itself, with no hormonal effect.¹

Why Hyaluronic Acid?

Significantly improves the ratio of vaginal superficial, intermediate, and parabasal cells (P<0.001) 3,7

Does not change endometrial thickness1,2

Significantly decreases vaginal pH (P<0.001) 3,7

Why Revaree?

Proven Effective

In a randomized, controlled, clinical trial evaluating 133 post-menopausal women, the active ingredient in Revaree, hyaluronic acid, was effective in relieving dryness at 9 days and 30 days.²

Safe & Well Tolerated

Revaree is an FDA cleared medical device and associated with no serious side effects. A version of the vaginal insert has been used by over one million women across Europe and Canada.⁴ It has also garnered a high level of patient satisfaction, with 92% compliance in an open, non-controlled clinical trial, and 95% satisfaction in a prospective, observational study.⁵,⁶

Revaree is not a contraceptive and is not compatible with condoms.

Easy-to-Use

Revaree eliminates the need for messy creams, dose measurements and applicators. Revaree comes in premeasured vaginal inserts for simple application and is administered directly into the vagina once every 2-3 days based on severity of symptoms.

As the vaginal tissue absorbs the hyaluronic acid, treatment begins working in as early as 9 days with continued improvement over time.²

Revaree can be used as frequently as needed depending on the evolution of symptoms and your recommendation.



Talk to your patients about Revaree

Recommend Revaree, a new approach to vaginal atrophy symptoms that's hormone-free, proven effective, and simple to use.

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© 2022 Bonafide Health, LLC

Bonafide®, Ristela®, Relizen®, and Serenol™ and their associated logos are trademarks of Bonafide Health, LLC. Revaree® and its associated logo are the exclusively licensed trademarks of JDS Therapeutics, LLC, the parent company of Bonafide Health, LLC. All third party trademarks are the property of their respective owners. Bonafide Health, LLC products are protected by a number of patents including, but not limited to: U.S. Patent Nos: 6,669,967 C1; 6,569,471 C1; and 9,028,890.

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
  • ¹ Shuai-Bin, Lui, et al. Gynecological Endocrinology. 2014.10:31:3, 208-213.
  • ² Chen J, et al. J Sex Med. 2013;10:1575-1584.
  • ³ Jokar A, et al. IJCBNM. 2016;4:69-78.
  • ⁴ Data on File. JDS Therapeutics.
  • ⁵ Origoni M, et al. Eur Rev Med Pharmacol Sci. 2016;20:4190-4195.
  • ⁶ Constantino D, et al. Eur Rev Med Pharmacol Sci. 2008; 12: 411-416.
  • ⁷ Ekin M, et al. Arch Gynecol Obstet. 2011; 12: 283:539–543.