Clinical trials determine if products work and are safe
Unlike many supplement brands that don’t test their products, Bonafide prioritizes safety and effectiveness by requiring clinical testing for all products. This approach gives customers and healthcare providers peace of mind knowing that our claims are supported by rigorous evidence
13,000
women have participated in Bonafide clinical studies and surveys †
35+ clinical trials and counting†
In an open-label trial of women with moderate-to-severe vaginal odor and no known infection¹
% of women reporting a reduction in odor
In the same study, 93% of women studied reported that they prefer Clairvee to other OTC products for vaginal symptoms¹
In a separate study, 75% of women reported improvements in vaginal itching and discharge vs. placebo in 15 days²
In a survey of more than 3,000 women, 96% of women plan to continue using Revaree.⁵
In a separate survey of more than 4,900 women, 85% reported they plan to continue taking Relizen.⁸
In three separate clinical studies, Ristela was shown to significantly improve Female Sexual Function Index (FSFI) scores after 2 months ⁹⁻¹¹
In a separate survey of more than 500 women, 75% experienced relief within 3 months and 82% reported that they plan to continue using Serenol¹⁴
In the same study, 100% of women told us they were satisfied with how healthy their facial skin looked.¹⁵⁻¹⁶
The gold standard in clinical trials
We use the gold standard of product testing: double-blinded placebo-controlled trials. Neither the participants nor the study team know who received the placebo or the supplement.
This rigorous research method is used to provide reliable and unbiased evidence of our product's effectiveness and safety. It helps healthcare providers make informed decisions about patient treatment and gives consumers confidence in the quality of the products they purchase.
Join our participant community
Our Bonafide research team is passionately committed to developing new formulations to further support women’s health. We invite you to join our participant community and discover how you can contribute to the testing of new products that address menopausal symptoms.
As a participant, you contribute to advancing women’s health research and gain an opportunity to access new innovative products before they come to market. Help us make a difference in the lives of countless women.
† Clinical trials were either conducted on Bonafide products or a key ingredient contained within Bonafide products.
¹ Results from an open-label clinical study.
² Russo R, Edu A, De Seta F. Arch Gynecol Obstet. 2018; 298(1):139-145.³ Liu SB, et al. Gynecol Endocrinol. 2015;31:208-213. Preclinical study.
⁴ Chen J, et al. J Sex Med. 2013:10:1575-1584. Results based on Revaree's main ingredient, Hyaluronic Acid.
⁵ Dweck A, et al. J Sex Med. 2022;19(Supplement 3):S26.⁶ Winther K, et al Climateric 205;8:162-170
⁷ Elia D, Mares P. Genesis. 2008;135:12-15.
⁸ Bernsley D, Sylla S, Komorowski J. Menopause. 2021;28(12):P-4.⁹ Bottari A, et al. Panminerva Med. 2012;54:3-9. 8-week, single-blinded trial in 83 post-menopausal women ages 45 to 55.
¹⁰ Stanislavov R and Rohdewald P. J Women's Health Care. 2014;3:1-6. 8-week, randomized, double-blind, placebo-controlled study conducted in 80 women ages 40-50.
¹¹ Bottari A, et al. Panminerva Med. 2012;54:3-9. 8-week, single-blinded trial in 83 post-menopausal women ages 45 to 55.
¹² Kellog Spadt S, et al. Effects of Ristela supplementation on female sexual satisfaction: an open-label trial. Menopause. 2019:26(12):1467-1468.¹³ Winther K. Hedman C., Curr Ther Res Clin Exp. 2002;63(5):344-353.
¹⁴ Results are from an optional, rolling online survey, conducted from July 2016 through November 2017, that included 500 customers who were taking Serenol for at least 3 months. Patients were compensated for completing the survey.¹⁵ Sylla S, et al. Current Developments in Nutrition. 2021; 5:Supplement_2:37.
¹⁶ Open-label extension data on file.
¹⁷ Kalman & Hewlings. J Clin Exp Dermatol Res. 2021;12:551.