We use the gold standard of clinical data
Other brands may use clinically tested ingredients. We go further.
Each of our formulas are vetted by randomized, double-blind, placebo-controlled clinical trials—the gold standard of health science research.
40+ clinical trials and counting†
Here are a few of our most recent results.
Clairvee®
Clairvee® relieves vaginal odor, itching, and discharge in women without an infection in just 15 days with continued relief over 6 months. 1,5*In an open-label trial of women with moderate-to-severe vaginal odor and no known infection:1
% of women reporting a reduction in odor
In the same study, 93% of women studied reported that they prefer Clairvee to other OTC products for vaginal symptoms.1
In a separate study, 75% of women reported improvements in vaginal itching and discharge vs. placebo in 15 days.5
Revaree®
Revaree® replenishes vaginal moisture with a hormone-free formula featuring hyaluronic acid.In a randomized, controlled, head-to-head clinical trial of hyaluronic acid, the main ingredient in Revaree, vs. estrogen cream, women reported:19
No significant difference vs estrogen cream (p>0.05)
Women also reported a significant reduction in pain during sex
In a survey of more than 3,000 women, 96% of women plan to continue using Revaree.23
Thermella®
Thermella® relieves hot flashes and night sweats at the source for cooling relief in just two weeks (with results that improve over time).*In a pooled analysis of two randomized, double-blind, placebo-controlled clinical trials:49
In a clinical study of women taking Thermella, 60% experienced improved sleep and 97% experienced improved quality of life.51
Ristela®
Ristela® significantly improves sexual function across all stages of a woman’s life.7,8,9*In an 8-week, open-label trial of pre, peri, and postmenopausal women with self-reported low sexual function:53
In three separate clinical studies, Ristela was shown to significantly improve Female Sexual Function Index (FSFI) scores after two months.
Serenol™
Serenol™ significantly reduces irritabillity, mood swings, uneasiness, and overall PMS severity*In a randomized, double-blind, placebo-controlled crossover study, women experienced:14
In a separate survey of more than 500 women, 75% experienced relief within three months and 82% reported they plan to continue using Serenol16
Silvessa®
Silvessa® improves the health and appearance of hair and skin affected by estrogen decline during menopause.*In an open-label trial on the ingredients in Silvessa:42
100% of women reported satisfaction with how healthy their facial skin looked.42 53
The gold standard in clinical trials
We use the gold standard of product testing: double-blinded placebo-controlled trials. Neither the participants nor the study team know who received the placebo or the supplement.
This rigorous research method is used to provide reliable and unbiased evidence of our product's effectiveness and safety. It helps healthcare providers make informed decisions about patient treatment and gives consumers confidence in the quality of the products they purchase.
Join our participant community
Our Bonafide research team is passionately committed to developing new formulations to further support women’s health. We invite you to join our participant community and discover how you can contribute to the testing of new products that address menopausal symptoms.
As a participant, you contribute to advancing women’s health research and gain an opportunity to access new innovative products before they come to market. Help us make a difference in the lives of countless women.
