Thermella®, Serenol™, and Clairvee®

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What is Thermella?

Thermella is a clinically studied, hormone-free supplement carefully formulated with curcumin extract, green tea extract, and spirulina extract, which work together to relieve menopausal hot flashes and night sweats. In a clinical study, Thermella reduced the interference of hot flashes on sleep.*

How does Thermella work?

Thermella works by targeting the signals in your body that cause hot flashes and night sweats to rebalance the body’s thermoregulatory center. As estrogen declines, the body loses its temperature balance as the signal that warms the body goes into overdrive, causing a hot flash. Thermella works by blocking this signal to restore balance for cooling relief.

How long does Thermella take to work?

Thermella works as quickly as just two weeks and 82% of women experienced a reduction in their hot flashes and night sweats in randomized, double-blind, placebo-controlled clinical trials. However, results with Thermella continue to improve over time. We recommend taking Thermella for at least three months to maximize relief and reductions in hot flash and night sweat symptoms.

Does Thermella have any side effects?

In double-blind, placebo-controlled trials, side effects of Thermella were comparable to placebo, and no serious adverse events were reported. However, every woman is different and if you have specific concerns, you should speak with your doctor or healthcare practitioner.

How do I know if Thermella is right for me?

Thermella is intended for women experiencing hot flashes or night sweats associated with menopause.

How often should I take Thermella?

Two tablets of Thermella should be taken once a day, with or without food.

Is the green tea extract in Thermella decaffeinated?

Yes, the green tea extract in Thermella is decaffeinated and contains less than 5mg of naturally occurring caffeine.

What is Serenol?

Serenol is a carefully formulated, hormone-free supplement for relieving emotional symptoms due to hormonal fluctuations like PMS and menopause, including irritability, mood fluctuations, and uneasiness.*

How does Serenol work?

The plant-based extract in Serenol is believed to work centrally in the body to reduce emotional symptoms due to hormonal fluctuations. Additionally, Serenol contains chromium picolinate, an essential mineral and insulin cofactor which improves glucose metabolism and appetite control.

How long does Serenol take to work?

Serenol takes time to work. In clinical studies, the majority of women experienced reduced irritability and mood swings results by month two, with improved results by month 3. While some women report feeling the benefits of Serenol earlier, we recommend you take Serenol every day for at least two months for best results.

Does Serenol have any side effects?

In clinical studies, any side effects reported were no different than those reported by people taking placebo tablets (sugar pills). If you have specific concerns, we recommend that you speak with your doctor.

How do I know if Serenol is right for me?

Serenol is intended for women who are experiencing emotional symptoms due to hormonal fluctuations like PMS and menopause, including irritability, mood fluctuations, and uneasiness.*

Are Bonafide products covered by health insurance? By Medicare/Medicaid?

At this time, our products are not covered by traditional insurance. That said, some healthcare HSA or FSA cards cover part or all of the cost of certain Bonafide products, so we recommend reaching out to your HSA/FSA provider to confirm if you can use your HSA or FSA funds.

Once you’ve confirmed that your HSA or FSA does cover Bonafide products, you should be able to place an order for any of our products; we’ve taken all of the necessary steps on our end to ensure you can access the proof of payment needed to file a reimbursement claim. We also recommend consulting your provider to determine what documentation is required to have your claim approved, as many providers require a Letter of Medical Necessity (LMN) in addition to a receipt.

What's the best way to place my FSA or HSA order?

First, double-check the balance on your FSA or HSA account and that your plan covers Bonafide products. You can place an order online, using your FSA or HSA card (as you would any other credit card), or by calling our Customer Care Team for assistance at 1-833-266-2343, Monday to Friday 9AM - 6PM ET.

What are the ingredients in Clairvee and how do they work?

Each Clairvee capsule contains: 

Clairvee® Vaginal Blend: Live, active probiotic strains, specific to the vaginal flora, shown to help balance and maintain a healthy vaginal microbiome. 

- 4 billion CFU lactobacilli acidophilus 

- 1 billion CFU lactobacilli rhamnosus 

Lactoferrin, 50mg: Key component of the natural vaginal defense system that works together with the Clairvee™ Vaginal Blend to help create a protective biofilm.

Folate (as L-methylfolate monosodium), 400mcg: Provides micronutrient support, folate may play a role in maintaining a healthy vaginal microbiome.

Clairvee Capsule™ Technology: Clairvee’s probiotic formulation is suspended in liquid folate and sealed in a second, outer capsule. This patented technology helps to protect the live probiotics and allows for a delayed release of the probiotics when ingested, thereby supporting optimal colonization and a reliable, high-quality formulation that does not require refrigeration.
 

Who can or should use Clairvee?

Clairvee can be used by any woman looking to sustain the good bacteria and yeast that balance their vaginal microbiome and maintain good vaginal health. Everyday factors can disrupt the vaginal microbiome in adult women at any age, such as sex, periods, menopause, diet, antibiotic use and many other external irritants.

How long does Clairvee take to work?

Clairvee has been clinically shown to restore and maintain balance of the vaginal microbiome in as early as 15 days. However, everyday factors like sex, menstruation, underwear fabrics, stress, hot weather, and diet can disrupt the vaginal microbiome. Multiple clinical trials show that regular use of Clairvee maintains a healthy, balanced vaginal microbiome month after month, and we recommend making Clairvee part of your monthly routine to maintain a healthy microbiome and prevent symptoms of imbalance over the long term.

Does Clairvee have any side effects?

Across four randomized, double-blinded, placebo controlled clinical studies, women on Clairvee reported no side effects or adverse events.

The probiotic strains in Clairvee have been designated GRAS, or Generally Recognized As Safe, by the FDA, meaning that there is a consensus of expert opinion that the strains are safe for their intended use.
 

How do I take Clairvee?

Clairvee is a once daily oral capsule that only needs to be taken for 15 consecutive days each month, given its uniquely powerful formulation. The remaining days are ‘off’ until next month. Probiotic protection continues to increase even on the days you’re not taking Clairvee. Just one oral capsule of Clairvee per day for 15 days maintains a balanced vaginal microbiome and provides month-long protection.

A 15-day supply of Clairvee is shipped at the same time every month to make it easy for you to incorporate Clairvee into your routine. Women should continue using Clairvee each month for as long as they want to maintain a healthy vaginal microbiome and prevent symptoms of vaginal imbalance. Please note that Clairvee should be taken orally and not inserted into the vagina.
 

Can I take Clairvee with other probiotics?

Yes, Clairvee is not known to negatively interact with other probiotics.

Can I use Clairvee if I’m lactose intolerant?

One ingredient in Clairvee, Lactoferrin, is derived from milk. Individuals with lactose intolerance concerns should speak to their healthcare practitioner before taking Clairvee.

Does Clairvee need to be refrigerated?

No, Clairvee does not need to be refrigerated. Probiotics are normally suggested to be refrigerated because in higher temperature conditions, probiotics can become hydrated. Once hydrated, probiotics become active and start working inside the capsule, and not in your body where they were designed to work. However, Clairvee was specifically formulated with probiotic strains that have been scientifically shown to be stable at room temperature for long periods of time. These shelf-stable probiotics do not require refrigeration because they are created in a way that protects them from becoming activated until they are in the body. Moreover, the Clairvee Capsule™ Technology further protects the probiotics from moisture, allowing for targeted delivery of the living probiotic strains to the body.

For added protection, Clairvee is also bottled in double-walled, moisture-tight containers designed specifically for probiotics that provide unparalleled protection and ensure stability and reliability.
 

Is Clairvee approved by the FDA (Food and Drug Administration)?

Clairvee is a dietary supplement, and the FDA does not approve dietary supplements. However, under the Dietary Supplement Health and Education Act of 1994 (DHSEA), the FDA regulates dietary supplements under a different set of regulations than those covering “conventional” foods and drug products.

At Bonafide, we are committed to ensuring our products are both safe and effective. All Bonafide products are scientifically validated and have been thoroughly tested for safety, efficacy, and potency. Together with our FDA-registered, NSF certified GMP† manufacturing facility, we rigorously test our products for contaminants such as microorganisms and heavy metals, like lead, to ensure that our products are safe and of the highest quality, because you deserve relief without compromise
 

Are Bonafide products covered by health insurance? By Medicare/Medicaid?

At this time, our products are not covered by traditional insurance. That said, some healthcare HSA or FSA cards cover part or all of the cost of certain Bonafide products, so we recommend reaching out to your HSA/FSA provider to confirm if you can use your HSA or FSA funds.

Once you’ve confirmed that your HSA or FSA does cover Bonafide products, you should be able to place an order for any of our products; we’ve taken all of the necessary steps on our end to ensure you can access the proof of payment needed to file a reimbursement claim. We also recommend consulting your provider to determine what documentation is required to have your claim approved, as many providers require a Letter of Medical Necessity (LMN) in addition to a receipt.
 

What's the best way to place my FSA or HSA order?

First, double-check the balance on your FSA or HSA account and that your plan covers Bonafide products. You can place an order online, using your FSA or HSA card (as you would any other credit card), or by calling our Customer Care Team for assistance at 1-833-266-2343, Monday to Friday 9AM - 6PM ET.