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Can Serenol™ Really Alleviate PMS Moodiness? We Took a Closer Look to Find Out

Written by Bridget Doherty

A dietary supplement called Serenol™ claims to alleviate irritability and mood swings that are associated with premenstrual syndrome. Can this actually be true?

PMS, also known as premenstrual syndrome, is a set of symptoms that around half of all women will experience during their lifetimes. It causes women to experience both physical and emotional symptoms before and during their periods.

Physical symptoms include bloating, tender breasts, headaches, and cramping. Many women also may experience soreness and cravings for specific foods. For the most part, these symptoms have long been able to be alleviated with some Midol and similar pain relief medications.

The emotional symptoms of PMS are a bit more difficult to pinpoint. Women who have emotional symptoms may experience brain fog, jitteriness, mood swings, and irritability. Some might also become prone to bouts of crying.

Unlike the physical symptoms of PMS, which can be easily alleviated with over-the-counter NSAIDs like ibuprofen, the emotional symptoms haven’t been so easy to take care of. It seems like Serenol may be here to change that.

If true, the supplement could help millions of women around the world feel like themselves again. So, does it actually help? We decided to take a look at the studies to find out what the numbers behind Serenol’s success had to say…

First, let’s talk about how Serenol works.

Serenol is a dietary supplement that is composed primarily of purified pollen extract, Chromax® chromium picolinate, and Royal Jelly, a milky substance that is produced by worker bees. Although it’s not entirely clear, it is thought that the pollen extract and Royal Jelly work together centrally in the body to help reduce many of the emotional symptoms of PMS, while chromium picolinate works to reduce certain physical symptoms of PMS*.

Unlike other potential treatments for PMS, Serenol is totally drug-free.

Serenol is completely drug-free.

Photo by Eye for Ebony:

In the past, women who were struggling with the “crazy-making” feeling of PMS would turn to prescription drug treatments to try to alleviate the symptoms. These, however, carry risks that most women do not want to deal with, and moreover, have not been found to be entirely effective in preventing symptoms from recurring.

Part of the reason why Serenol has become popular is because it’s a drug-free supplement whose ingredients have still been shown to help women deal with that emotional turmoil side of PMS*(1).

This is how we decided to find out the truth behind Serenol’s efficacy.

It’s not fair to judge really anything by a single-time use or by the minimum amount of time it should be taken. Like many other supplements, Serenol’s active ingredients take time to fully show their effects. To ensure that we understood the full power of the ingredients, we decided to take a look at what real women had to say after approximately three months of use.

Ready to find out what the proof might be? We were, too! So, let’s take a look at what studies have shown.

Here’s what women who’ve tried Serenol had to say after three months of use.

Here’s what women who’ve tried Serenol had to say after three months of use.

Photo by Omar Lopez:

For the most part, studies have been overwhelmingly positive. One clinical study had shown that the overall severity of irritability, moodiness, and uneasiness in women who took it regularly was reduced*(1).

But that doesn’t really give you any data, does it? You’re probably wondering how well it worked.

In a double-blind, placebo-controlled crossover study, women who were given placebo for two cycles then were switched to Serenol noted a 70 percent reduction in irritability and a 71 percent reduction in mood swings (1).

Of course, this doesn’t really mean much of anything if the symptoms were reduced for only a handful of women. A separate survey of nearly 300 actual Serenol users showed that approximately 77 percent of participants who took Serenol for three cycles saw a reduction in their symptoms (2).

In other words, it works for most women who take it regularly and give it time to work. For women who are struggling with the emotional symptoms of PMS, Serenol could be just the key to restoring that sense of normalcy.

Surprisingly, mood swings and irritability aren’t the only thing that Serenol’s ingredients have been shown to improve.

One thing we’ve noticed is that Serenol has a lot of perks that make it great for women who suffer from PMS. Along with the two most bothersome emotional symptoms, its ingredients have also been shown to reduce food cravings and water retention*(1). For women who tend to get down in the dumps when they are dealing with PMS-related weight gain, this adds yet another awesome way to feel better.


It’s a supplement women and doctors both believe in—and obviously they have good reason!

Serenol is a supplement both women and doctors believe in.

Photo by Joanna Nix:

Another good indicator of how well Serenol can work is found in the sheer number of people who back it up. In a survey conducted by Serenol, 87 percent of women who used it would suggest it to friends and family. Not only that, but 83 percent of its users also plan to continue using it to relieve their symptoms. Women love Serenol—and that bodes well for PMS sufferers looking to feel like their old selves again.

Doctors, too, give Serenol a big thumbs up. Over 3,000 doctors recommend it to their patients, with over 1,600 of those being gynecologists. Needless to say, if you’re looking for a drug-free way to get rid of those awful PMS crazies, Serenol will definitely be a doctor-approved method you should consider trying. Don’t trust us? Go back and give those numbers another look.

If you want to try Serenol, it’s easier than ever before.

Taking Serenol is easy as can be, and so is ordering it—you can order it directly through Bonafide's website. Using it is also designed to be as stress-free as possible. Those interested in trying it out are instructed to take it as a twice-daily supplement for at least two months straight.

Once you decide you love it, it can be difficult to actually remember to order it from month-to-month, especially if you have a busy lifestyle. To make things easier, Serenol offers a monthly subscription service that gives you a regular, automated delivery for $40 per month.

Serenol is all about simplifying your life and alleviating symptoms that make it difficult during your time of the month. Life is already complicated, so why should your solution to PMS symptoms be, too? 

  1. Winther K, Henman C. Curr Ther Res Clin Exp. 2002; 63 (5): 344-353.

  2. Results are from an optional, rolling online survey, conducted from July 2016 through November 2017, that included 290 customers who were taking Serenol for at least 3 months. Patients who completed the survey were compensated with a $10 gift card for their opinions about Serenol.

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* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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