Managing shifting hormones during the menopause transition is often tricky, especially when access to treatments like estrogen patches hinges on supply and demand.
Fortunately, safe and effective options for menopause symptom management are growing, opening the door for other solutions when estrogen patch availability is limited. Bonafide Chief Medical Officer, Dr. Alyssa Dweck, provides some insights on estrogen patch alternatives and offers guidance on what to do if you’ve missed an estrogen patch dose, following an initial discussion with your healthcare provider.
Missed an Estrogen Patch? Here’s What You Need to Know
Since only a few manufacturers produce estrogen patches, shortages from any one producer may greatly impact supply.1,2 This gap between supply and demand may leave many women with “out-of-stock” notifications at pharmacy store counters, explains Dr. Dweck.
“Estrogen patches are a hot commodity these days, with ‘patch wars anecdotes’ even breaking out in some pharmacy parking lots,” she continues. “The current shortage of estrogen patches is, in part, due to supply chain issues, and availability seems to vary by pharmacy or chain.”
What to Do When Estrogen Patches Aren’t Available
Dr. Dweck goes on to assure women that there are other menopause treatment options to consider in the meantime if you’re thinking of a change. Women who have missed or are running low on estrogen patches may choose to consider the following options.
Consider Switching Brands
Be sure to ask your pharmacist about switching brands or trying a generic version of the estrogen patch you use, if you’re open to that option, and have discussed it with your provider.3 Since brands may use different adhesives or preservatives, as well as specific hormonal ingredients, it’s important to ask questions and follow the guidance of a pharmacist and/or healthcare provider when exploring potential alternatives.4
Ask About Other Delivery Formats
In some situations, Dr. Dweck says switching to other forms of estrogen could help some women manage symptoms in the interim during shortages. It’s best to work with a healthcare provider and/or pharmacist when thinking about switching to alternative methods, as safe and effective menopause symptom management isn’t the same for every woman.
Other forms of estrogen delivery formats include:5,6,7,8,9
- Gel—Applied daily for absorption through the skin, gels needs time to dry after applying, and estrogen levels peak a few hours later before gradually declining throughout the day.
- Mist (spray)—Applied daily to the skin, where it is absorbed into the bloodstream. Absorption varies depending on skin contact and application.
- Systemic dose vaginal ring—Inserted into the vagina and administered every 90 days in two doses.
- Oral tablet—Taken daily by mouth. Unlike with skin application, oral estrogen is processed through the liver, which may influence side effects for some women.
Talk Though Dosing Options
You may think rationing your current supply of estrogen patches is an effective strategy. While it’s possible to cut some estrogen patches, in a pinch—it should only be done under the guidance of a licensed physician, cautions Dr. Dweck.10 This may not work with all patches, including combination patches, as the medication is layered and applied unevenly across the patch.11 A healthcare provider can guide you in altering the dose of your remaining patches to help you manage your symptoms while supplies are limited.
“While cutting a patch into equal parts is a viable option to achieve a safe and effective estrogen dose for an individual, this is appropriate for matrix-designed patches only,” adds Dr. Dweck. “Reservoir release transdermal systems are not amenable to cutting and may not deliver a reliable dosage.” As mentioned, be sure to check with your provider first.
Your Healthcare Provider Can Help You Navigate Your Options
If you’ve missed a patch or are considering a different form of estrogen, make sure to work with your healthcare provider or pharmacist to find the safest, most effective option for you. Every menopause journey is unique—your treatment plan should be, too.
Resources
- https://health.yahoo.com/your-body/womens-health/menopause/articles/whats-really-driving-estrogen-patch-181345251.html
- https://www.everydayhealth.com/womens-health/estrogen-patches-in-short-supply-is-there-a-workaround/
- https://www.nhs.uk/medicines/hormone-replacement-therapy-hrt/oestrogen-tablets-patches-gel-and-spray/common-questions-about-oestrogen-tablets-patches-gel-and-spray/
- https://www.nbcnews.com/health/womens-health/estrogen-patches-menopause-hard-find-hormone-replacement-therapy-rcna257224#
- https://www.mayoclinic.org/drugs-supplements/estradiol-topical-application-route/description/drg-20573786
- https://www.sciencedirect.com/science/article/abs/pii/S0378512299000213
- https://www.mayoclinic.org/drugs-supplements/estradiol-transdermal-route/description/drg-20075306
- https://www.drugs.com/pro/femring.html
- https://newsroom.heart.org/news/women-taking-oral-estrogen-hormones-may-have-increased-risk-of-high-blood-pressure
- https://www.bcchildrens.ca/media/4431/download?inline
- https://pmc.ncbi.nlm.nih.gov/articles/PMC6454296/