Ristela® CLINICAL TRIALS

The clinical evidence behind Ristela®

Ristela is a daily supplement designed to help women achieve enhanced arousal and intimate pleasure through increased blood flow to the vagina. Below is a summary of the peer-reviewed clinical evidence supporting the efficacy of Ristela.


  • 5 clinical studies
  • Includes randomized, double-blind placebo controlled trials
  • Peer-reviewed & published in indexed journals

Below is a sample of the peer-reviewed clinical evidence supporting the efficacy of Ristela involving women with difficulty during intimacy, including perimenopausal women. These studies have been published in Journal Women's Health Care, Minerva Genecologica, and The Journal of Sexual Medicine.

Bonafide requires clinical testing for most products. This approach gives both our customers and healthcare providers confidence that our products are safe and effective and that our claims are supported by rigorous evidence. 

Ristela for Sexual Satisfaction

Ristela® TRIAL 1

Women experienced a 75% improvement in sexual satisfaction on Ristela after 2 months

After 2 months on Ristela, perimenopausal women experienced a 74% improvement in ability to orgasm and 75% improvement in sexual satisfaction and arousal. Ristela enhances the response to sexual stimulation by increasing blood flow to the vaginal area. Ristela was found to promote powerful antioxidant activity.

Stanislavov R and Rohdewald P. J Women’s Health Care. 2014;3:1-6. 8-week, randomized, double-blind, placebo-controlled study conducted in 80 women ages 40-50.

FIND THE STUDYOpens in a new window.
  • RCT

    randomized, double-blind, placebo-controlled trial

  • 80 women

    study size

  • 75%

    improvement in sexual satisfaction and arousal

  • Published

    in Journal Women’s Health Care

Ristela® TRIAL 2

Women experienced a 122% increase in sexual function after 2 months

In an open-label trial of 100 premenopausal women, participants experienced a 122% increase in sexual function after 2 months on Ristela.

Bottari A, et al. Minerva Genecol. 2013;65:435-444. 8-week, active-controlled lifestyle study in 100 premenopausal women ages 37- 45

FIND THE STUDYOpens in a new window.
  • Open label

    open-label clinical trial

  • 100 women

    study size

  • 122%

    increase in sexual function

  • Published

    in Minerva Genecologica

Ristela® TRIAL 3

Women experienced a 61% increase in sexual function after 2 months

In a randomized, placebo-controlled trial of 83 postmenopausal women participants experienced a 61% increase in sexual function after 2 months on Ristela.

Bottari A, et al. Panminerva Med. 2012;54:3-9. 8-week, randomized, single-blind, placebo-controlled study in 83 postmenopausal women ages 45-55

FIND THE STUDYOpens in a new window.
  • RCT

    randomized, double-blind, placebo-controlled trial

  • 83 women

    study size

  • 61%

    increase in sexual function

  • Published

    in Minerva Genecologica

Ristela® TRIAL 4

86% of women want to continue using Ristela

In an open-label trial of 30 women, 86% of participants wanted to continue using Ristela.

Kellogg-Spadt et al. J Sex Med. 2020;17(7)3:S259-S260.

FIND THE STUDYOpens in a new window.
  • Open label

    open-label clinical trial

  • 30 women

    study size

  • 86%

    want to continue using Ristela

  • Published

    in The Journal of Sexual Medicine

Learn more about Ristela

See the full product page, ingredients, and how to get started.

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